GHK‑Cu – 50mg

Permagainz GHK-Cu is a synthetic tripeptide–copper complex supplied strictly for scientific and in-vitro research. The compound consists of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (GHK) complexed with a divalent copper ion (Cu²⁺).

In laboratory studies, GHK-Cu is frequently used to examine metal-peptide binding dynamics, enzyme activity regulation, and cellular signalling mechanisms linked to extracellular matrix (ECM) maintenance and tissue modelling.

Each vial contains 50 mg of lyophilised GHK-Cu, manufactured in ISO-accredited facilities to guarantee high purity, consistency, and analytical traceability.

Chemical Background / Research Profile

The chemical formula of GHK-Cu is C₁₄H₂₄CuN₆O₄, with a molecular weight of approximately 403.9 g/mol.

This peptide–metal complex is of particular research interest because it plays a role in copper transport and regulation within biological systems. In vitro, GHK-Cu is studied to:

• Investigate copper-mediated enzymatic processes such as lysyl oxidase and superoxide dismutase activity.

• Examine collagen synthesis and cell-matrix communication.

• Model oxidative-stress modulation and gene-expression signalling in cell culture assays.

Its stability and binding affinity make it ideal for controlled experiments involving metal ion chelation, antioxidant enzyme systems, and biochemical interaction mapping.

Purity and Quality Assurance

Every batch of Permagainz GHK-Cu is validated to a minimum purity of ≥ 98 %, confirmed through High-Performance Liquid Chromatography (HPLC), mass spectrometry (MS), and inductively coupled plasma mass spectrometry (ICP-MS) for copper quantification.
Manufacturing follows Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) within clean-room environments.

Each vial is securely sealed, labelled, and supplied with a Certificate of Analysis (CoA) specifying structure, purity, batch number, and expiry date for complete traceability.

Laboratory Handling and Storage

• Store at 2–8 °C in a sealed, light-protected container.

• For long-term storage, freezing at –20 °C is recommended.

• Before opening, allow the vial to reach ambient temperature to prevent condensation.

• Reconstitute under aseptic conditions using sterile bacteriostatic water or other laboratory-grade solvent.

• Avoid repeated freeze–thaw cycles and dispose of unused material according to institutional chemical-waste policies.

Researchers should handle all materials wearing appropriate PPE—gloves, laboratory coat, and eye protection—and perform procedures in approved laboratory environments.

Safety, Compliance and Restrictions

GHK-Cu is not a medicinal product, not approved for human or veterinary use, and must never be administered or used for diagnostic or therapeutic purposes.

It is supplied solely for laboratory and in-vitro research in accordance with MHRA, REACH, and COSHH regulations governing non-medicinal chemical substances.

Permagainz ensures all materials meet UK and EU quality and documentation standards, providing researchers with dependable compounds for reproducible experimental results.