GHRP-2 (5mg)

Permagainz GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide supplied exclusively for in-vitro and laboratory research.

It is part of the growth hormone secretagogue (GHS) family and is used by researchers to study pituitary receptor activation, ghrelin signalling, and peptide-receptor binding kinetics in controlled environments.

Each vial contains 5 mg of lyophilised GHRP-2, produced under ISO-accredited sterile conditions to ensure analytical consistency, purity, and traceability.

Chemical Background / Research Profile

GHRP-2 has the chemical formula C₄₅H₅₅N₉O₆ and a molecular weight of approximately 817.0 g/mol. It is a synthetic peptide analogue designed to mimic endogenous ghrelin-like activity through selective agonism of the growth hormone secretagogue receptor type 1a (GHS-R1a).

In research settings, GHRP-2 is used to explore:

• Signal transduction mechanisms associated with GHS-R activation.

• Growth hormone release modelling in cultured pituitary cell systems.

• Receptor-ligand binding affinity and intracellular calcium mobilisation.

• Peptide stability and degradation rates under physiological conditions.

The compound is frequently used alongside other GHS analogues, such as GHRP-6, Ipamorelin, and Hexarelin, to compare receptor selectivity, structural stability, and peptide performance in laboratory environments.

Purity and Quality Assurance

All Permagainz research peptides are validated to ≥ 98 % purity, verified using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS).

Production follows Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) standards in ISO-certified clean-room facilities.

Each vial is supplied sterile-sealed and accompanied by a Certificate of Analysis (CoA) confirming purity, structure, batch number, and expiry date.

Laboratory Handling and Storage

• Store at 2–8 °C, away from light and humidity.

• For long-term preservation, freeze at –20 °C.

• Allow the vial to reach room temperature before opening to prevent condensation.

• Reconstitute using sterile bacteriostatic water or another appropriate laboratory-grade solvent under aseptic conditions.

• Avoid repeated freeze–thaw cycles.

• Dispose of unused material according to institutional chemical safety and biosafety procedures.

Laboratory staff must wear appropriate PPE (gloves, coat, eye protection) and work in a clean, controlled research environment when handling peptide materials.

Safety, Compliance and Restrictions

GHRP-2 is supplied strictly for research and laboratory use only. It is not a pharmaceutical, not for human or veterinary use, and must not be administered, consumed, or used for diagnostic or therapeutic purposes.

Permagainz operates in full compliance with MHRA, REACH, and COSHH regulations governing the safe handling and distribution of research chemicals.

All materials are traceable, batch-tested, and intended solely for professional use in authorised research facilities.

Through consistent quality control and transparent scientific documentation, Permagainz provides GHRP-2 of exceptional analytical integrity, supporting reproducible studies in peptide biochemistry, receptor pharmacology, and molecular signalling.