YK‑11 (Myostine) – 5mg

Permagainz YK-11 (Myostine) is a synthetic steroidal Selective Androgen Receptor Modulator (SARM) analogue supplied strictly for in-vitro and laboratory research.

It is a partial androgen receptor (AR) agonist that also acts as a myostatin signalling inhibitor, making it a valuable compound for scientific studies investigating androgen receptor pharmacology, cellular signalling, and myogenic gene regulation.

Each vial contains 5 mg of YK-11, produced in ISO-accredited clean-room facilities under Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) standards to ensure exceptional purity, reproducibility, and traceability.

Chemical Background / Research Profile

The chemical formula of YK-11 is C₂₅H₃₄O₆, with a molecular weight of approximately 430.54 g/mol.

YK-11 belongs to the myostatin-modulating subclass of SARMs and is structurally related to dihydrotestosterone (DHT), while remaining functionally distinct due to its partial agonism at the androgen receptor.

In research settings, YK-11 is used to:

• Examine androgen receptor binding affinity and partial agonist behaviour.

• Study inhibition of myostatin (GDF-8) signalling and related protein pathways.

• Investigate myogenic differentiation, cell proliferation, and gene transcription in in-vitro models.

• Explore ligand-receptor selectivity and structure–activity relationships (SARs) in synthetic AR modulators.

Its unique dual mechanism—combining AR activation with myostatin pathway suppression—makes YK-11 an important reference compound in receptor pharmacology and muscle cell molecular biology research.

Purity and Quality Assurance

Permagainz YK-11 is verified to ≥ 98 % purity, confirmed using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS).

Every batch is produced and packaged under ISO-certified laboratory conditions, ensuring sterility and chemical integrity.

Each vial is supplied with a Certificate of Analysis (CoA) confirming purity, molecular structure, batch number, and expiry date for full documentation compliance and traceability.

Laboratory Handling and Storage

• Store at 20–25 °C in a cool, dry, and dark environment.

• Protect from moisture, light, and heat.

• Dissolve using suitable analytical-grade solvents under aseptic laboratory conditions.

• Avoid repeated freeze–thaw cycles and cross-contamination.

• Dispose of any unused compound in accordance with institutional COSHH and chemical-safety protocols.

Researchers must handle all SARM materials using appropriate PPE (gloves, lab coat, and protective eyewear) within authorised facilities.

Safety, Compliance and Restrictions

YK-11 (Myostine) is not a medicinal product, not approved for human or veterinary use, and must not be consumed, injected, or used diagnostically or therapeutically.
It is supplied solely for scientific and in-vitro research.

Permagainz operates in full compliance with MHRA, REACH, and COSHH standards regulating the lawful handling of non-medicinal research chemicals.

All products are batch-tested, documented, and traceable, ensuring reliability and ethical compliance for professional laboratory use.

Through precision synthesis, stringent quality control, and verified purity, Permagainz provides YK-11 5 mg as a dependable research compound for advanced studies into androgen receptor activity, myostatin inhibition, and molecular muscle biology.