Andarine (S‑4) – 25mg

Permagainz Andarine (S-4) is a non-steroidal Selective Androgen Receptor Modulator (SARM) supplied strictly for in-vitro and laboratory research.

It is a synthetic compound developed to study androgen receptor (AR) binding, tissue-selective activity, and molecular signalling mechanisms associated with anabolic and androgenic pathways.

Each vial contains 25 mg of Andarine (S-4), produced under ISO-certified clean-room conditions to ensure high purity, batch consistency, and analytical traceability for research applications.

Chemical Background / Research Profile

The chemical formula of Andarine is C₁₉H₁₈F₃N₃O₆S, with a molecular weight of approximately 441.36 g/mol.

It belongs to the class of aryl propionamide SARMs, designed to selectively bind to the androgen receptor while displaying tissue-specific agonist or partial-agonist behaviour.

In research studies, Andarine (S-4) is used to:

• Examine androgen receptor activation in vitro.

• Investigate AR-mediated gene transcription and signal transduction.

• Study ligand–receptor selectivity and tissue-dependent anabolic responses.

• Evaluate receptor binding affinity, metabolic stability, and structure–activity relationships (SAR).

Because of its strong affinity for the androgen receptor and partial agonist properties, S-4 serves as a key reference compound for receptor modulation, ligand design, and cellular pathway analysis in controlled research environments.

Purity and Quality Assurance

Every batch of Permagainz Andarine (S-4) is verified to ≥ 98 % purity using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS).

Production is carried out in ISO-accredited laboratories following Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) protocols.

Each vial is sterile-sealed and supplied with a Certificate of Analysis (CoA) confirming batch number, molecular structure, purity, and expiry date.
This ensures complete traceability and compliance with UK research documentation requirements.

Laboratory Handling and Storage

• Store at 20–25 °C in a cool, dry, and dark environment.

• Keep sealed until required to prevent contamination.

• Dissolve using a suitable analytical-grade solvent under aseptic conditions.

• Avoid repeated freeze–thaw cycles if stored in solution form.

• Dispose of all materials in accordance with institutional chemical and environmental safety policies.

Personnel must wear PPE (gloves, coat, and protective eyewear) and handle all SARM compounds within authorised laboratory facilities following COSHH safety standards.

Safety, Compliance and Restrictions

Andarine (S-4) is not a pharmaceutical product, not approved for human or veterinary use, and must not be consumed, injected, or used for diagnostic or therapeutic purposes.
It is supplied strictly for scientific and in-vitro research.

Permagainz operates in compliance with MHRA, REACH, and COSHH regulations governing the sale and handling of non-medicinal research materials.

All SARMs are batch-tested, fully documented, and intended exclusively for legitimate research conducted by qualified professionals.

Through rigorous quality control, validated analytical testing, and transparent documentation, Permagainz provides Andarine (S-4) 25 mg as a reliable, research-grade compound suitable for in-vitro studies of androgen receptor selectivity, molecular pharmacology, and cellular regulation.