SR‑9009 (Stenabolic) – 10mg

£49.00

REV‑ERBα/β ligand for gene‑expression studies.

SKU: PERM-SR9009-10 Category: Tags: , , ,
Description

Permagainz SR-9009 (Stenabolic) is a synthetic research compound classified as a REV-ERBα (NR1D1) agonist, supplied strictly for in-vitro and laboratory research.

It is a non-steroidal molecule used by researchers to investigate circadian rhythm regulation, mitochondrial biogenesis, and metabolic gene expression under controlled laboratory conditions.

Each vial contains 10 mg of high-purity SR-9009, produced in ISO-accredited clean-room facilities to guarantee analytical consistency, purity, and reproducibility for scientific research use.

Chemical Background / Research Profile

The chemical formula of SR-9009 is C₂₀H₂₄ClN₃O₄S, with a molecular weight of approximately 437.94 g/mol.

It belongs to the class of synthetic REV-ERBα nuclear receptor agonists, compounds that interact with transcriptional repressors involved in the regulation of metabolic and circadian genes.

In research environments, SR-9009 is used to:

  • Study REV-ERBα and REV-ERBβ receptor activation and their effects on gene transcription.

  • Investigate mitochondrial activity, energy expenditure, and oxidative metabolism.

  • Examine cellular circadian rhythm regulation and metabolic feedback mechanisms.

  • Evaluate ligand selectivity, binding kinetics, and structure–activity relationships (SARs) of REV-ERB receptor agonists.

Because of its well-defined receptor selectivity and reproducible signalling behaviour, SR-9009 serves as a valuable reference compound in molecular biology, metabolic research, and chronobiology studies.

Purity and Quality Assurance

Each batch of Permagainz SR-9009 is verified to ≥ 98 % purity using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) analysis.

Manufacturing follows Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) within ISO-certified facilities.

Each vial is sterile-sealed and supplied with a Certificate of Analysis (CoA) confirming purity, batch number, molecular identity, and expiry date to ensure traceability and compliance with research documentation standards.

Laboratory Handling and Storage

  • Store at 20–25 °C in a dry, dark environment.

  • Protect from direct sunlight, heat, and humidity.

  • Dissolve using analytical-grade solvents under aseptic conditions.

  • Avoid contamination and repeated freeze–thaw cycles.

  • Dispose of unused material following institutional COSHH and chemical-safety protocols.

Researchers must wear PPE (gloves, coat, and protective eyewear) and handle SR-9009 only within authorised laboratory environments.

Safety, Compliance and Restrictions

SR-9009 (Stenabolic) is not a medicinal product, not approved for human or veterinary use, and must not be ingested, injected, or applied for diagnostic or therapeutic purposes.

It is supplied exclusively for scientific and in-vitro research.

Permagainz operates in full compliance with MHRA, REACH, and COSHH regulations covering the handling and distribution of non-medicinal research compounds.

All materials are batch-tested, traceable, and fully documented, ensuring lawful and ethical use in professional research settings.

Through verified purity, controlled synthesis, and transparent documentation, Permagainz provides SR-9009 10 mg as a dependable research compound for the study of REV-ERBα receptor pharmacology, metabolic gene regulation, and cellular energy pathways.

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